Georgia Mother and Her Children Infected Twice with H1N1
Many cities around the world are reporting re-infections, including US geography in and around Georgia and New York.
---
Does an antibody set from a previous infection protect me? Not always.
Under what conditions do my antibodies protect me? An antibody response is very protective if timely, in high quantity and matched to the intruding virus.
Viral strains change and PF11 is changing rapidly on the areas that the human body uses for recognition. If you were trying to identify a villain that you only saw once from the rear, then you’d have to use the clothing as your key. The villain knows that you only saw his clothes and not his face. Will the criminal change clothes? Yes. Will this virus? Yes.
For some reason, people have been led to believe that “getting” PF11 now will be an iron-clad protection from later versions of the disease. Medical professionals seem to rely on this thinking though their training demonstrates otherwise. We do have a new Influenza season every year and they do see many patients more than one time in a season. They do create a new vaccine every year and that vaccine does fail to match or fail to seroconvert much of the time. They do know that Influenza is variable, but they don’t realise just how variable because they haven’t taken the time to study the ΣPF11 genetic sequences.
We received a response from a friend who is a medical professional noting that her child had been exposed from an extended family member, developed symptoms and appeared to have fully recovered. We rejoiced that they had been spared significant suffering, but were concerned about the triumphant tone of the message.
Busy people sometimes do not regard the facts well unless the facts fit into their busy schedule. In fact, busy people sometimes fail to put their own knowledge to work in their own families? A virus like PF11 does not care about your schedule.
We responded with facts about this particular unprecedented pandemic:
Are you doing anything to ensure that all of you are developing a robust antibody response over the next 21-30 days? Remember that due to weakened host immune responses a strong percentage of people who are exposed will not seroconvert to a fully protective antibody profile. Even an individual who does build a basic profile will face future PF11 specimens that have escaped the antibody profiles in that individual host and host family. That future specimen could occur in less than a month from the initial infection due to the observed PF11 enhanced genetic acquisition trait and the ample circulating diversity in any single geography. I refer you to the Three Time Loser in 1918. If the host is traveling, then multiple exposures to variant antigens are ensured.
Maintaining a properly regulated innate immune function is extremely important even after an individual appears to have successfully recovered from the initial exposure cycle. The antibodies created, if they do seroconvert a protective set, can only be called into action via the initial innate immune response. The virus must be recognised by the body before any adaptive immune response will be mounted. A properly regulated innate immune response serves that detection function, acting as a coordinator, determining if matching antibody exists and calling it into action. Secondarily, a significant count of children and young adults are on file as having appeared to recover and then relapsing to become fatal cases. This PF11 virus may quiesce the immune system at any phase, early or mid-stream. The relapse potential is a fact with this viral reservoir.
Influenza Flux between swine, bird and man creates a mismatched host-disease interchange that is highly variable in outcomes.
Succeeding in Round 1 against this virus is great, but now the virus knows that you can block a left jab and will try something new. As PF11, under the cover of cold weather, learns more about the North American hosts, PF11 will exploit the weaknesses just as the reservoir did in South America in July and August with more than 1,000 deaths in Brasil alone.
Diligence in the Round 2 will determine our success. You are in a 15 round endurance match. This virus is well-trained and well-stocked in his corner. Will we stay on our toes and move one step ahead of the virus or will we rest on our heels leaving our chin exposed for the knockout punch?
Each adult will decide for themselves, but remember that the children are dependent on the adults who head their families and their communities to decide for them.
For additional background on the clinical and epidemiological observational facts concerning Pandemic Influenza H1N1, please refer to the Table of Contents for PF11 Trends & Issues, Mid-Term.
Showing posts with label risk group. Show all posts
Showing posts with label risk group. Show all posts
2009-10-08
2009-09-24
TamiFlu Shortage in Prime Risk Group Occurs Only 4 Weeks After School Starts
Children congregating in schools and universities appear to be the highest risk group for PF11 infection. School has been in session for approximately 4 weeks. Very little cold weather has occurred in the United States at this time.
Roche announced today that a shortage exists in their production of TamiFlu for children (liquid form). The company advised pharmacists to grind the adult pill-based drug and adjust the dosage for children.
Health officials say that priority will be given to those hospitalised. If TamiFlu is effective only if used within 48 hours of symptoms and more than half of some populations do not present with the official case definition of fever, then few who are hospitalised will be within that 48 hour window. Hospitalisation will primarily occur after significant viral replication time has passed (>48 hours) and the patient presents with incapacitating signals. This prioritisation appears to be misguided given the Facts.
Please review our research section discussing proposed mediation measures for further information.
For additional background on the clinical and epidemiological observational facts concerning Pandemic Influenza H1N1, please refer to the Table of Contents for PF11 Trends & Issues, Mid-Term.
Roche announced today that a shortage exists in their production of TamiFlu for children (liquid form). The company advised pharmacists to grind the adult pill-based drug and adjust the dosage for children.
Health officials say that priority will be given to those hospitalised. If TamiFlu is effective only if used within 48 hours of symptoms and more than half of some populations do not present with the official case definition of fever, then few who are hospitalised will be within that 48 hour window. Hospitalisation will primarily occur after significant viral replication time has passed (>48 hours) and the patient presents with incapacitating signals. This prioritisation appears to be misguided given the Facts.
- TamiFlu resistance is geographically widespread in PF11 as demonstrated in the sequence databases.
- PF11 has not yet begun to peak.
- Public health officials expect cold weather combined with the school gatherings to spur the case count substantially.
Please review our research section discussing proposed mediation measures for further information.
For additional background on the clinical and epidemiological observational facts concerning Pandemic Influenza H1N1, please refer to the Table of Contents for PF11 Trends & Issues, Mid-Term.
Subscribe to:
Posts (Atom)

