Showing posts with label FirstWave. Show all posts
Showing posts with label FirstWave. Show all posts

2009-10-08

Can My Child Be Re-Infected If They've Already Suffered from Pandemic Influenza H1N1?

Georgia Mother and Her Children Infected Twice with H1N1

Many cities around the world are reporting re-infections, including US geography in and around Georgia and New York.

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Does an antibody set from a previous infection protect me?  Not always.

Under what conditions do my antibodies protect me?  An antibody response is very protective if timely, in high quantity and matched to the intruding virus.

Viral strains change and PF11 is changing rapidly on the areas that the human body uses for recognition.  If you were trying to identify a villain that you only saw once from the rear, then you’d have to use the clothing as your key. The villain knows that you only saw his clothes and not his face.  Will the criminal change clothes?  Yes.  Will this virus? Yes.

For some reason, people have been led to believe that “getting” PF11 now will be an iron-clad protection from later versions of the disease.  Medical professionals seem to rely on this thinking though their training demonstrates otherwise.  We do have a new Influenza season every year and they do see many patients more than one time in a season.   They do create a new vaccine every year and that vaccine does fail to match or fail to seroconvert much of the time.  They do know that Influenza is variable, but they don’t realise just how variable because they haven’t taken the time to study the ΣPF11 genetic sequences.

We received a response from a friend who is a medical professional noting that her child had been exposed from an extended family member, developed symptoms and appeared to have fully recovered.  We rejoiced that they had been spared significant suffering, but were concerned about the triumphant tone of the message.

Busy people sometimes do not regard the facts well unless the facts fit into their busy schedule.  In fact, busy people sometimes fail to put their own knowledge to work in their own families?  A virus like PF11 does not care about your schedule.

We responded with facts about this particular unprecedented pandemic:

Are you doing anything to ensure that all of you are developing a robust antibody response over the next 21-30 days?  Remember that due to weakened host immune responses a strong percentage of people who are exposed will not seroconvert to a fully protective antibody profile.  Even an individual who does build a basic profile will face future PF11 specimens that have escaped the antibody profiles in that individual host and host family.  That future specimen could occur in less than a month from the initial infection due to the observed PF11 enhanced genetic acquisition trait and the ample circulating diversity in any single geography.  I refer you to the Three Time Loser in 1918.  If the host is traveling, then multiple exposures to variant antigens are ensured.

Maintaining a properly regulated innate immune function is extremely important even after an individual appears to have successfully recovered from the initial exposure cycle.  The antibodies created, if they do seroconvert a protective set, can only be called into action via the initial innate immune response.  The virus must be recognised by the body before any adaptive immune response will be mounted.  A properly regulated innate immune response serves that detection function, acting as a coordinator, determining if matching antibody exists and calling it into action.  Secondarily, a significant count of children and young adults are on file as having appeared to recover and then relapsing to become fatal cases.  This PF11 virus may quiesce the immune system at any phase, early or mid-stream.  The relapse potential is a fact with this viral reservoir.

Influenza Flux between swine, bird and man creates a mismatched host-disease interchange that is highly variable in outcomes.


Succeeding in Round 1 against this virus is great, but now the virus knows that you can block a left jab and will try something new.  As PF11, under the cover of cold weather, learns more about the North American hosts, PF11 will exploit the weaknesses just as the reservoir did in South America in July and August with more than 1,000 deaths in Brasil alone.

Diligence in the Round 2 will determine our success.  You are in a 15 round endurance match.  This virus is well-trained and well-stocked in his corner.  Will we stay on our toes and move one step ahead of the virus or will we rest on our heels leaving our chin exposed for the knockout punch?

Each adult will decide for themselves, but remember that the children are dependent on the adults who head their families and their communities to decide for them.



For additional background on the clinical and epidemiological observational facts concerning Pandemic Influenza H1N1, please refer to the Table of Contents for PF11 Trends & Issues, Mid-Term.


Please visit GeneWurx.com for insight into the latest published studies.

GeneWurx.com

2009-08-25

PF11 Trends & Issues, Mid-Term, Table of Contents

This analytical paper presented in a blog format attempts to synopsise more than one thousand point studies over a five-year period directed at Pandemic Influenza.  Revisions and updates will be made on this blog as the pandemic progresses. 

Read the sections first that most interest you and then return to read the complete work.  Using the ordered links in this Table of Contents will allow the reader a deeper comprehension as categorical terms are detailed sequentially at the point of introduction.

Please contact me with any concerns so that I may evaluate for revisions.
  1. Why should I care about Pandemic Influenza H1N1?
  2. What features does PF11 engage inside a human body?
  3. What human outcomes has PF11 demonstrated in this FirstWave?
  4. What part of our population is affected by PF11?
  5. What is the Nation Level Response to PF11?
  6. Where is PF11 going?
  7. Environmental Factors
  8. Genetic Acquisition Point Studies
  9. Glossary


Please visit GeneWurx.com for insight into the latest published studies.

GeneWurx.com

What features does PF11 engage inside a human body?

PF11 moves fast, wears camouflage and is comfortable operating in almost any terrain.

At our institute, we categorise FirstWave PF11 alongside the H5N1 and the 1918 pandemic strains as an Interferon-Deranging, Rapid Replicating Virus strain (IDRRV). The similarities between PF11, today’s Avian Influenza H5N1 and the 1918 strains are quite unappealing, but must be communicated. The SecondWave viral strain cannot be characterised until we see a stable genotype in the coming months because this present virus is persistent in acquiring new genetic material. Although most Influenza-suspect pandemics / plagues that we’ve reviewed in history demonstrate marked clinical differences in the first and second waves, we prefer to measure rather than speculate on this “once in a century” event. Science measures. Measurement may only occur during or after an event.

This virus carries the genetics for extreme illness, sudden death and long-term sequelae (complications) for survivors . . . and PF11 has connections to advance genetically. The circulating strains have clinically demonstrated a destructive multi-tropism (6 major human tissue types at last count), an ability to temporarily deactivate the immune system (interference of a required early cytokine-mediated process) and a swift speed of replication. By having a “head-start” on the body after immediately blunting the immune system and then using the added feature of rapid reproduction, PF11 initially gains a solid grasp in the throat and lungs.

Then the multi-tropism, like H5N1 and 1918, gives the PF11 virus an ability to attack multiple organ systems individually or simultaneously creating a wider battleground inside the host than a typical immune system can manage, culminating at times in a fatal outcome. Many patients demonstrate no fever until after they have deeply progressed (50% - Chile, 33% - Mexico), showing that the first warning signal for Influenza may not occur. The virus has the binding ability to enter many types of organs and has now been documented as using the bloodstream for transport.

What is FirstWave PF11 doing today?





For additional background on the clinical and epidemiological observational facts concerning Pandemic Influenza H1N1, please refer to the Table of Contents for PF11 Trends & Issues, Mid-Term.


Please visit GeneWurx.com for insight into the latest published studies.

GeneWurx.com